PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT3G51910.1
Common NameAT-HSFA7A, F4F15.20, HSF09, HSFA7A
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family HSF
Protein Properties Length: 272aa    MW: 31776 Da    PI: 6.4315
Description heat shock transcription factor A7A
Gene Model
Gene Model ID Type Source Coding Sequence
AT3G51910.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HSF_DNA-bind110.71e-34301202101
                   HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXXXX CS
  HSF_DNA-bind   2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkellekik 98 
                   Fl+k++e+++d+++++++sw++ g+sfvv+d ++f++ +Lp++Fkhsnf+SF+RQLn+YgF+k++ e+         weF++++F  g+++ll++ik
   AT3G51910.1  30 FLTKTFEMVDDPNTDHIVSWNRGGTSFVVWDLHSFSTILLPRHFKHSNFSSFIRQLNTYGFRKIEAER---------WEFANEEFLLGQRQLLKNIK 117
                   9****************************************************************999.........******************** PP

                   XXX CS
  HSF_DNA-bind  99 rkk 101
                   r++
   AT3G51910.1 118 RRN 120
                   *97 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM004151.6E-5526119IPR000232Heat shock factor (HSF)-type, DNA-binding
SuperFamilySSF467856.12E-3426119IPR011991Winged helix-turn-helix DNA-binding domain
Gene3DG3DSA:1.10.10.101.3E-3626119IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF004472.2E-3030119IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000562.3E-193053IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000562.3E-196880IPR000232Heat shock factor (HSF)-type, DNA-binding
PROSITE patternPS0043406993IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000562.3E-198193IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009408Biological Processresponse to heat
GO:0009644Biological Processresponse to high light intensity
GO:0032268Biological Processregulation of cellular protein metabolic process
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0009005anatomyroot
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 272 aa     Download sequence    Send to blast
MMNPFLPEGC DPPPPPQPME GLHENAPPPF LTKTFEMVDD PNTDHIVSWN RGGTSFVVWD  60
LHSFSTILLP RHFKHSNFSS FIRQLNTYGF RKIEAERWEF ANEEFLLGQR QLLKNIKRRN  120
PFTPSSSPSH DACNELRREK QVLMMEIVSL RQQQQTTKSY IKAMEQRIEG TERKQRQMMS  180
FLARAMQSPS FLHQLLKQRD KKIKELEDNE SAKRKRGSSS MSELEVLALE MQGHGKQRNM  240
LEEEDHQLVV ERELDDGFWE ELLSDESLAS TS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2ldu_A3e-242811918120Heat shock factor protein 1
5d5u_B3e-242811927129Heat shock factor protein 1
5d5v_B3e-242811927129Heat shock factor protein 1
5d5v_D3e-242811927129Heat shock factor protein 1
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1112118LKNIKRR
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.438610.0root| seed
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO184094500.0
Genevisible252081_at0.0
Expression AtlasAT3G51910-
AtGenExpressAT3G51910-
ATTED-IIAT3G51910-
Functional Description ? help Back to Top
Source Description
TAIRmember of Heat Stress Transcription Factor (Hsf) family
UniProtTranscriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE).
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT3G51910.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT3G51910
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAL0497110.0AL049711.3 Arabidopsis thaliana DNA chromosome 3, BAC clone F4F15.
GenBankCP0026860.0CP002686.1 Arabidopsis thaliana chromosome 3, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_190759.10.0heat stress transcription factor A-7a
SwissprotQ9SV120.0HFA7A_ARATH; Heat stress transcription factor A-7a
TrEMBLD7LTZ91e-172D7LTZ9_ARALL; AT-HSFA7A
STRINGAT3G51910.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM12562899
Representative plantOGRP9617233
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Nover L, et al.
    Arabidopsis and the heat stress transcription factor world: how many heat stress transcription factors do we need?
    Cell Stress Chaperones, 2001. 6(3): p. 177-89
    [PMID:11599559]
  3. Port M, et al.
    Role of Hsp17.4-CII as coregulator and cytoplasmic retention factor of tomato heat stress transcription factor HsfA2.
    Plant Physiol., 2004. 135(3): p. 1457-70
    [PMID:15247379]
  4. Contento AL,Kim SJ,Bassham DC
    Transcriptome profiling of the response of Arabidopsis suspension culture cells to Suc starvation.
    Plant Physiol., 2004. 135(4): p. 2330-47
    [PMID:15310832]
  5. Gieg
    Coordination of nuclear and mitochondrial genome expression during mitochondrial biogenesis in Arabidopsis.
    Plant Cell, 2005. 17(5): p. 1497-512
    [PMID:15829605]
  6. Vanderauwera S, et al.
    Genome-wide analysis of hydrogen peroxide-regulated gene expression in Arabidopsis reveals a high light-induced transcriptional cluster involved in anthocyanin biosynthesis.
    Plant Physiol., 2005. 139(2): p. 806-21
    [PMID:16183842]
  7. Vergnolle C, et al.
    The cold-induced early activation of phospholipase C and D pathways determines the response of two distinct clusters of genes in Arabidopsis cell suspensions.
    Plant Physiol., 2005. 139(3): p. 1217-33
    [PMID:16258011]
  8. Xin Z,Zhao Y,Zheng ZL
    Transcriptome analysis reveals specific modulation of abscisic acid signaling by ROP10 small GTPase in Arabidopsis.
    Plant Physiol., 2005. 139(3): p. 1350-65
    [PMID:16258012]
  9. Nicola
    Large-scale analysis of mRNA translation states during sucrose starvation in arabidopsis cells identifies cell proliferation and chromatin structure as targets of translational control.
    Plant Physiol., 2006. 141(2): p. 663-73
    [PMID:16632591]
  10. Nishizawa A, et al.
    Arabidopsis heat shock transcription factor A2 as a key regulator in response to several types of environmental stress.
    Plant J., 2006. 48(4): p. 535-47
    [PMID:17059409]
  11. Charng YY, et al.
    A heat-inducible transcription factor, HsfA2, is required for extension of acquired thermotolerance in Arabidopsis.
    Plant Physiol., 2007. 143(1): p. 251-62
    [PMID:17085506]
  12. Larkindale J,Vierling E
    Core genome responses involved in acclimation to high temperature.
    Plant Physiol., 2008. 146(2): p. 748-61
    [PMID:18055584]
  13. Cartagena JA, et al.
    The Arabidopsis SDG4 contributes to the regulation of pollen tube growth by methylation of histone H3 lysines 4 and 36 in mature pollen.
    Dev. Biol., 2008. 315(2): p. 355-68
    [PMID:18252252]
  14. Guo J, et al.
    Genome-wide analysis of heat shock transcription factor families in rice and Arabidopsis.
    J Genet Genomics, 2008. 35(2): p. 105-18
    [PMID:18407058]
  15. Sugio A,Dreos R,Aparicio F,Maule AJ
    The cytosolic protein response as a subcomponent of the wider heat shock response in Arabidopsis.
    Plant Cell, 2009. 21(2): p. 642-54
    [PMID:19244141]
  16. Nishizawa-Yokoi A, et al.
    HsfA1d and HsfA1e involved in the transcriptional regulation of HsfA2 function as key regulators for the Hsf signaling network in response to environmental stress.
    Plant Cell Physiol., 2011. 52(5): p. 933-45
    [PMID:21471117]
  17. Ikeda M,Mitsuda N,Ohme-Takagi M
    Arabidopsis HsfB1 and HsfB2b act as repressors of the expression of heat-inducible Hsfs but positively regulate the acquired thermotolerance.
    Plant Physiol., 2011. 157(3): p. 1243-54
    [PMID:21908690]